以下是潓美全球82篇基础临床研究及链接。提示：国际期刊网站缓存速度较慢，建议耐心等待查看！基于广大患者的关注，潓美梳理更新全球论文研究成果，涉及呼吸系统疾病、肿瘤医学、脑与心智、脊髓与神经、肌肉与骨骼、泌尿与生殖、缺血再灌注、眼耳鼻、过敏/免疫/血液、肠胃道、代谢系统等多个领域。（2023年8月止）

呼吸系统疾病

慢阻肺

1.Geng et al. 吸入高浓度H2对大鼠慢性阻塞性肺病的效. Protective Effects of Hydrogen Inhalation on Rat Model of Chronic Obstructive Pulmonary Disease. 现代生物医学进展2015, 15(18):3401-3405

链接：

https://xueshu.baidu.com/usercenter/paper/show?paperid=1abd20117c72816e9342d583e708e12b&site=xueshu_se

哮喘

2.Chang et al. 吸入高浓度H2对大鼠支气管哮喘的治疗作用. Therapeutical effects of hydrogen inhalation on rat model of bronchial asthma. 国际呼吸杂志. Int J Respir 2015, 35(3):179-182

链接：http://www.cqvip.com/qk/95715a/201503/663703101.html

尘肺

5.Gong et al. 氢气对环卫工人雾霾暴露肺保护性作用的研究. Protective effects of hydrogen inhalation on sanitation workers exposed to Haze. 中华结核和呼吸杂志 2016, 39(12): 916-923.

链接：http://www.cqvip.com/qk/92952x/2016012/670980986.html

慢阻肺

9.Liu et al. 吸入H2能减缓香烟烟雾诱导的大鼠模型COPD肺部疾病的发展. Inhalation of H2 slows the development of COPD lung disease induced by smoking in rat model. International Journal of COPD 2017;12:1309–1324

链接：https://www.ascleway.org/video/en/MYS/D9.pdf

慢阻肺

15.Lu et al. 吸入H2能防止香烟烟熏诱导之慢性阻塞性肺病. Hydrogen gas inhalation protects against cigarette smoke-induced COPD development in mice. Journal of Thoracic Disease 2018;10(6):3232-3243

链接：https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051853/

睡眠呼吸暂停

17.Guan et al. H2可降低慢性间歇性低氧(由阻塞性睡眠呼吸暂停症所致)的高血压. Hydrogen gas reduces chronic intermittent hypoxia‐induced hypertension by inhibiting sympathetic nerve activity and increasing vasodilator responses via the antioxidation. Journal of Cellular Biochemistry 2019;120(3):3998-4008

链接：https://pubmed.ncbi.nlm.nih.gov/30259991/

慢性间歇性低氧肝脏氧化损伤

19.Yang et al. H2对慢性间歇性氧大鼠肝脏氧化应激损伤的改善作用. Improvement of hydrogen on liver oxidative stress injury in chronic intermittent hypoxia rats.中国应用生理学杂志2018;34(1):61-63

链接：https://xueshu.baidu.com/usercenter/paper/show?paperid=b8ced687093a3b2d8ef39109f2989b9d&site=xueshu_se

气管狭窄

20.Zhou et al. 吸入氢氧混合气体能降低气管狭窄患者的气道阻力. Breathing Hydrogen-Oxygen mixture decreases inspiratory effort in patients with tracheal stenosis. Respiration 2019;97(1):42-51

链接：https://karger.com/res/article-abstract/97/1/42/290773/Breathing-Hydrogen-Oxygen-Mixture-Decreases?redirectedFrom=PDF

过敏性鼻炎

26. Fang et al. 氢气缓解过敏性鼻炎.Beneficial effects of hydrogen gas inhalation on a murine model of allergic rhinitis. Experimental and Therapeutic Medicine 2018 ;16(6):5178-5184

链接：https://www.spandidos-publications.com/etm/16/6/5178

哮喘

31.Huang et al. 吸入氢气可增强哮喘模型肺泡巨噬细胞吞噬作用. Hydrogen gas inhalation enhances alveolar macrophage phagocytosis in an ovalbumin-induced asthma model. International Immunopharmacology 2019;74:105646

链接：https://www.sciencedirect.com/science/article/abs/pii/S1567576918313638

哮喘

36.Zhang et al. 吸入氢气可减轻过敏性哮喘小鼠的气道炎症和氧化应激. Inhalation of hydrogen gas attenuates airway inflammation and oxidative stress in allergic asthmatic mice. Asthma Research and Practice 2018;4:3

链接：https://asthmarp.biomedcentral.com/articles/10.1186/s40733-018-0040-y

肺损伤

77.Yin et al. 氢气减轻脂多糖诱导的小鼠急性肺损伤和炎症反应. Hydrogen gas alleviates lipopolysaccharide-induced acute lung injury and inflammatory response in mice. Journal of Inflammation. 2022;19:16

链接：

https://journal-inflammation.biomedcentral.com/articles/10.1186/s12950-022-00314-x

肺纤维化

45.Gao et al. 氢吸入通过抑制TGF-β1路径来减轻肺纤维化.( Hydrogen Inhalation Attenuated Bleomycin-Induced Pulmonary Fibrosis by Inhibiting Transforming Growth factor-β1 and Relevant Oxidative Stress and Epithelial-To-Mesenchymal Transition .) Hydrogen attenuates BLM-induced pulmonary fibrosis by inhibiting TGF-β1. Experimental Physiology 2019;104(12):1942-1951.

链接：https://physoc.onlinelibrary.wiley.com/doi/full/10.1113/EP088028

新冠肺炎

46.Guan et al. 预防和管理冠状病毒疾病的策略2019. Strategies for the prevention and management of coronavirus disease 2019. European Respiratory Journal. 2020 

链接：https://erj.ersjournals.com/content/55/4/2000597.short

新冠肺炎

49.Guan et al. 在最近的一项多中心，开放标签临床试验中，氢氧气混合气体吸入改善了2019年冠状病毒病患者的疾病严重程度和呼吸困难. Hydrogen/oxygen mixed gas inhalation improves disease severity and dyspnea in patients with Coronavirus disease 2019 in a recent multicenter, open-label clinical trial. Journal of Thoracic Disease 2020;12(6):3448-3452

链接：https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330772/

新冠肺炎

75.Lin et al. 有助于减缓 COVID-19 病人症状与减少住院时间的医用高浓度氢氧气之回顾. 北市医学杂志. Taipei City Medical Journal. 2022.

链接：https://baijiahao.baidu.com/s?id=1771152861185917021&wfr=spider&for=pc

新冠肺炎

51.Grace Russell et al. 分子氢辅助治疗COVID - 19感染概述. An Overview of SARS-CoV-2 (COVID-19) Infection: The Importance of Molecular Hydrogen as an Adjunctive Therapy. REACTIVE OXYGEN SPECIES 2020;10(28):150-165 (泰勒)

链接：http://www.mlpla.org.cn/dzfw/yhjy/xgzl/202002/P020200223744071552675.pdf

新冠肺炎

52.Yang et al. 氢：COVID-19患者的潜在新辅助疗法. Hydrogen: A Potential New Adjuvant Therapy for COVID-19 Patients. Front Pharmacol 2020; 11: 543718 (杨福勋)

链接：https://www.frontiersin.org/articles/10.3389/fphar.2020.543718/full

新冠肺炎

53.Wei Liu, Wei-Jie Guan, Nan-Shan Zhong. 中国对抗COVID-19的策略与进展. Strategies and Advances in Combating COVID-19 in China. Engineering 2020;6 :1076-1084

链接：https://www.sciencedirect.com/science/article/pii/S209580992030285X

肺损伤

61.Feng et al.氢通过芳烃受体改善亚急性暴露于高浓度 PM2.5 的大鼠模型的肺损伤。Hydrogen ameliorates lung injury in a rat model of subacute exposure to on centrated ambient PM2.5 via Aryl hydrocarbon receptor. Int Immunopharmacol. 2019 Dec;77:105939.

链接：https://www.sciencedirect.com/science/article/abs/pii/S1567576919310252

新冠肺炎

64.Tyler W. LeBaron et al. 通过分子氢疗法对抗 COVID-19 的氧化应激和炎症：机制和前景Combating Oxidative Stress and Inflammation in COVID-19 by Molecular Hydrogen Therapy: Mechanisms and Perspectives. Oxid Med Cell Longev. 2021:5513868.

链接：https://www.hindawi.com/journals/omcl/2021/5513868/

新冠肺炎

65.Wei et al. 新型冠状病毒肺炎诊疗方案（试行第七版）. Diagnosis and Treatment Protocol for Novel Coronavirus Pneumonia (Trial Version 7). Chin Med J (Engl). 2020,133(9):1087-1095.

链接：

https://baike.baidu.com/item/%E6%96%B0%E5%9E%8B%E5%86%A0%E7%8A%B6%E7%97%85%E6%AF%92%E8%82%BA%E7%82%8E%E8%AF%8A%E7%96%97%E6%96%B9%E6%A1%88/24341924?fr=aladdin

新冠肺炎

80.Zeng et al. 氢氧疗法对普通 COVID-19 患者的影响：倾向评分匹配的病例对照研究. Effect of hydrogen-oxygen therapy for ordinary COVID-19 patients: a propensity-score matched case-control study. BMC Infectious Diseases. 2023;23(1):440

链接：https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-023-08424-4

心脏功能障碍

28.Zhao et al. 氢氧混合改善间歇性缺氧大鼠心功能障碍. Hydrogen and oxygen mixture to improve cardiac dysfunction and myocardial pathological changes induced by intermittent hypoxia in rats. Oxidative Medicine and Cellular Longevity 2019 ;2019:7415212

链接：https://www.hindawi.com/journals/omcl/2019/7415212/

慢性间歇性缺氧引起肾脏损伤

29.Guan et al. 氢气减少铁超载且减轻慢性间歇性缺氧引起的肾脏损伤. Hydrogen gas alleviates chronic intermittent hypoxia-induced renal injury through reducing iron overload. Molecules 2019;24(6)1184

链接：https://www.mdpi.com/1420-3049/24/6/1184

慢性间歇性缺氧肾损害

30.Guan et al. 氢通过促进自噬作用和减轻细胞凋亡，降低慢性间歇性低氧引起的肾损害. Hydrogen protects against chronic intermittent hypoxia induced renal dysfunction by promoting autophagy and alleviating apoptosis. Life Sciences 2019 ;225:46-54

链接：https://www.sciencedirect.com/science/article/abs/pii/S0024320519302553

携氧弥散

72.Tang et al. 电解水是高海拔地区有效的氧气来源. Electrolysis of water is an effective source of oxygen at high altitude. J Transl Med. 2022;20(1):242.

链接：https://link.springer.com/article/10.1186/s12967-022-03443-2

脑与神经

抑郁症

11.Gao et al.氢分子可能缓解压力. Molecular hydrogen increases resilience to stress in mice. Scientific Reports 2017;7(1):9625

链接：https://www.nature.com/articles/s41598-017-10362-6

脑损伤

40.Wang et al. 吸入高浓度氢气对大鼠创伤性脑损伤的影响. Effects of inhaling high concentration hydrogen on traumatic brain injury in rats. 临床麻醉学杂志2019;35(10):1013-1017

链接：http://www.lcmzxzz.com/ch/reader/view_abstract.aspx?flag=1&file_no=201910018&journal_id=lcmzxzz

脑损伤

68.Li et al. 分子氢减轻创伤性脑损伤后的肺损伤：细胞焦亡和细胞凋亡. Molecular hydrogen alleviates lung injury after traumatic brain injury: Pyroptosis and apoptosis. Eur J Pharmacol. 2022;914:174664.

链接：https://www.sciencedirect.com/science/article/abs/pii/S0014299921008207

术后谵妄

78.Lin et al. 氢气改善老年人术后谵妄和认知功能障碍. Hydrogen gas treatment improves postoperative delirium and cognitive dysfunction in elderly noncardiac patients. Journal of Personalized Medicine, 2023, 13(1): 67

链接：https://www.mdpi.com/2075-4426/13/1/67

蛛网膜下腔出血

41.Zhang et al. 氢气疗法可改善蛛网膜下腔出血大鼠的存活率和神经功能缺损. Hydrogen gas therapy improves survival rate and neurological deficits in subarachnoid hemorrhage rats: a pilot study. Medical Gas Research 2019;9(2):74-79

链接：https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607870/

糖尿病

44.Li et al. 高浓度氢对糖尿病大鼠脑外伤后神经功能的影响. Effects of a high concentration of hydrogen on neurological function after traumatic brain injury in diabetic rats. Brain Research. 2020 Mar 1;1730:146651.

链接：https://www.sciencedirect.com/science/article/abs/pii/S000689932030007X

植物人

69.Huang et al. 氢气吸入促进脑出血持续植物人患者恢复：病例报告. Hydrogen inhalation promotes recovery of a patient in persistent vegetative state from intracerebral hemorrhage: A case report and literature review. World J Clin Cases. 2022;10(4):1311-1319

链接：http://www.jiank.com/cjxw/content_0315879117.html

神经认知障碍

18.Li et al. H2能通过抑制氧化应激改善慢性间歇性低氧导致的神经认知障碍. Hydrogen ameliorates chronic intermittent hypoxia-induced neurocognitive impairment via inhibiting oxidative stress . Brain Research Bulletin 2018;143:225-233.

链接：https://www.sciencedirect.com/science/article/abs/pii/S0361923018305197

阿兹海默

82.Dan et al. 多奈哌齐联合氢氧混合气吸入治疗阿尔茨海默病的疗效：一项回顾性研究. Efficacy of donepezil plus hydrogen-oxygen mixture inhalation for treatment of patients with Alzheimer disease: A retrospective study. Medicine. 2023 Jul 28;102(30):e34382.

链接：https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378857/

脊髓

脊髓损伤

16.Chen et al. 吸入高浓度H2对小鼠脊髓损伤的保护作用.Inhalation of Hydrogen of Different Concentrations Ameliorates Spinal Cord Injury in Mice by Protecting Spinal Cord Neurons from Apoptosis, Oxidative Injury and Mitochondrial Structure Damages. Cell Physiol Biochem.2018;47(1):176-190

链接：https://pubmed.ncbi.nlm.nih.gov/29763919/

泌尿与生殖

子宫内膜异位症

肾结石

3.Peng et al. H2吸入减轻小鼠草酸钙沉积及肾脏氧化应激水平. Inhalation of hydrogen gas ameliorates glyoxylate-induced calcium oxalate deposition and renal oxidative stress in mice. International Journal of Clinical and Experimental Pathology 2015;8(3):2680-9

链接：https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440082/

8. Y. He et al. 吸入H2对子宫内膜异位症的影响. Effects of Hydrogen Gas Inhalation on Endometriosis in Rats. Reproductive Sciences 2017;24(2):324-331

链接：https://journals.sagepub.com/doi/abs/10.1177/1933719116655622

肾结石

43.Lu et al. 基于UPLC / MS的代谢组学研究了氢气吸入对草酸钙诱发的肾损伤小鼠的保护作用.UPLC/MS-Based Metabolomics Investigation of the Protective Effect of Hydrogen Gas Inhalation on Mice with Calcium Oxalate-Induced Renal Injury 2018:41 1652-1658

链接：https://www.jstage.jst.go.jp/article/bpb/41/11/41_b18-00307/_article/-char/ja/

关节

关节炎

42.Li et al. 氢气对单关节炎大鼠的保护作用.Protective effects of hydrogen on monoarthritis rats. DOI：10.16781/j.0258-879x.2019.11.1258

链接：https://pesquisa.bvsalud.org/portal/resource/pt/wpr-838084

肿瘤医学

肺癌

13. Wang et al. H2透过对SMC3的影响抑制肺癌进展. Hydrogen gas inhibits lung cancer progression through targeting SMC3. Biomedicine & Pharmacotherapy 2018;104:788-797

链接：https://xueshu.baidu.com/usercenter/paper/show?paperid=17500rg00c4f0vm0ud220pk0bb454447&site=xueshu_se

非小细胞肺癌

14. Wang et al. H2干预抑制非小细胞肺癌生长的作用及其机制研究. Effect and mechanism of hydrogen suppressing non-small cell lung cancer. 国际呼吸杂志2018;38(8):561-565

链接：https://rs.yiigle.com/cmaid/1038409

卵巢癌

23.Shang et al. H2在治疗卵巢癌中的潜在效用.Therapeutic potential of molecular hydrogen in ovarian cancer. Translational Cancer Research 2018;7(4):988-995

链接：https://pdfs.semanticscholar.org/feb2/0ac8981a0a100a6bad2b546ead5b791a41d5.pdf

胶质瘤

33.Liu et al. 氢分子通过诱导胶质瘤干细胞分化及抑制胶质瘤的生长. Molecular hydrogen suppresses glioblastoma growth via inducing the glioma stem-like cell differentiation. Stem Cell Research & Therapy 2019;10(1):145

链接：https://link.springer.com/article/10.1186/s13287-019-1241-x

胆囊癌

34.Chen et al. 氢气治疗转移性胆囊癌个案报导. Hydrogen gas therapy induced shrinkage of metastatic gallbladder cancer: A case report. World J Clin Cases 2019 ; 7(15): 2065-2074

链接：https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695532/

癌症

35.Chen et al. 氢控制癌症的“现实世界调查”：82位晚期癌症患者的随访报告.“Real world survey” of hydrogen-controlled cancer: a follow-up report of 82 advanced cancer patients. Medical Gas Research 2019;9(3):115-121

链接：https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779007/

鼻咽癌

37.Chen et al. 氢氧疗法可减轻鼻咽癌放疗所致的听力损失. Hydrogen–oxygen therapy can alleviate radiotherapy-induced hearing loss in patients with nasopharyngeal cancer. Annals of Palliative Medicine 2019;8(5):746-751

链接：https://apm.amegroups.org/article/view/32168

胆囊癌

38.Chen et al. 胆囊癌患者氢吸入后假性进展性缓解. A Gallbladder Carcinoma Patient With Pseudo-Progressive Remission After Hydrogen Inhalation. World Journal of Clinical Cases 2019;12 :8645-8651

链接：https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804672/

非小细胞肺癌

39.Chen et al. 吸入氢气治疗非小细胞肺癌脑转移完全消失. Brain Metastases Completely Disappear in Non-Small Cell Lung Cancer Using Hydrogen Gas Inhalation: A Case Report. OncoTargets and Therapy 2019;12 :11145-11151

链接：https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927257/

非小细胞肺癌

48.Chen et al. 氢疗法可用于控制晚期非小细胞肺癌患者的肿瘤进展并减轻药物不良反应。. Hydrogen therapy can be used to control tumor progression and alleviate the adverse events of medications in patients with advanced non-small cell lung cancer. Medical Gas Research 2020;10(2):75-80

链接：https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885710/

肺癌

55.Niu et al. 氢气対病人胸腔镜肺癌根治术后肺部并发症发生的影响. Effect of hydrogen on occurrence of pulmonary complications after thoracoscopic radical resection of lung cancer. Chin J Anesthesiol 2020;40(8):907-910

链接：https://pesquisa.bvsalud.org/portal/resource/pt/wpr-869963

胃癌

56.Zhu et al. 氢通过调节lncRNA MALAT1 / miR-124-3p / EZH2轴抑制胃癌细胞的增殖和迁移. Hydrogen inhibits the proliferation and migration of gastric cancer cells by modulating lncRNA MALAT1/miR-124-3p/EZH2 axis. Cancer Cell International 2021;21(1):70.

链接： https://cancerci.biomedcentral.com/articles/10.1186/s12935-020-01743-5

非小细胞肺癌 

57.Chen et al. 一项两周的氢气吸入可以显著逆转晚期非小细胞肺癌的适应性和先天性免疫系统衰老患者：一项自我对照研究. Two weeks of hydrogen inhalation can significantly reverse adaptive and innate immune system senescence patients with advanced non-small cell lung cancer: a self-controlled study. Medical Gas Research 2020;10(4):149-154

链接：https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092147/

肿瘤

62.Chen et al.氢肿瘤学的叙述性回顾：从现实世界调查到现实世界证据。A narrative review of hydrogen oncology: from real world survey to real world evidence. Med Gas Res. 2020;10(3):130-133.

链接：https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8086626/

鼻咽癌

70.Kong et al. 氢气吸入治疗对鼻咽癌放疗后听力损失的影响. Effect of Hydrogen Inhalation Therapy on Hearing Loss of Patients With Nasopharyngeal Carcinoma After Radiotherapy. Front Med. 2022;9:828370

链接：https://www.frontiersin.org/articles/10.3389/fmed.2022.828370/full

缺血再灌注

脑缺血再灌注损伤

4.Chi et al. 氢气的生物安全性研究及对大鼠脑缺血再灌注损伤的保护作用. Inhalation of water electrolysis-derived hydrogen ameliorates cerebral ischemia-reperfusion injury in rats - A possible new hydrogen resource for clinical use. Neuroscience 2016;335:232-41

链接：https://www.sciencedirect.com/science/article/abs/pii/S0306452216303943

视网膜缺血再灌注

6.Wang et al. 氢治疗对视网膜缺血再灌注神经损伤的保护作用. Postconditioning with inhaled hydrogen promotes survival of retinal ganglion cells in a rat model of retinal ischemia/reperfusion injury. Brain Research 2016;1632:82-90

链接：https://www.sciencedirect.com/science/article/abs/pii/S0006899315009543

脑缺血再灌注损伤

7.Xia et al.高浓度氢气吸入对大鼠局灶性脑缺血再灌注损伤脑皮质神经细胞凋亡及凋亡相关蛋白表达的影响. Effects of inhaling high concentrations hydrogen gas on neuronal apoptosis and the expression of apoptosis related proteins in the cortical region of rats with cerebral ischemia reperfusion injury. Guangdong Medical Journal 2016,37(24):3645-3649

链接：http://www.cqvip.com/qk/90176x/201624/670992974.html

心脏缺血性再灌注损伤

10.Chen et al. 吸入高浓度H2保护小鼠心脏免受缺血再灌注损伤. High-concentration hydrogen protects mouse heart against ischemia/reperfusion injury through activation of the PI3K/Akt1 pathway. Scientific Reports 2017;7(1):14871

链接：https://www.nature.com/articles/s41598-017-14072-x

肝脏缺血再灌注损伤

12.Li et al. 吸入高浓度H2通过A2A受体介导的PI3K-Akt通道改善肝脏缺血再灌注损伤. Inhalation of high-concentrated H2 improves hepatic ischemia reperfusion injury through A2A receptor-mediated PI3K/Akt pathway. Biochemical Pharmacology 2017;130:83-92

链接：https://www.ascleway.org/video/en/MYS/D12.pdf

褥疮/压疮

22.Fang et al. 氢气吸入治疗压疮. Hydrogen gas inhalation protects against cutaneous ischaemia/reperfusion injury in a mouse model of pressure ulcer. Journal of Cellular and Molecular Medicine 2018;22(9):4243-4252

链接：https://onlinelibrary.wiley.com/doi/full/10.1111/jcmm.13704

内皮祖细胞损伤

71.Mu et al. 氢气通过PI3K/AKT/eNOS 通路修复 LPS 诱导的内皮祖细胞损伤. Hydrogen Repairs LPS-Induced Endothelial Progenitor Cells Injury via PI3K/AKT/eNOS Pathway. Front. Pharmacol 2022;13:1-12

链接：https://www.frontiersin.org/articles/10.3389/fphar.2022.894812/full

抗氧化

47.Fang et al. 分子氢通过激活Nrf2信号传导保护人类黑素细胞免受氧化应激.

Molecular Hydrogen Protects Human Melanocytes from Oxidative Stress by Activating Nrf2 Signaling. Journal of Investigative Dermatology 2020;S0022-202X(20)31206-9

链接：https://www.sciencedirect.com/science/article/pii/S0022202X20312069

脑缺血再灌注损伤

67.Wan et al. 吸入高浓度氢气对大鼠脑缺血再灌注损伤的影响. Effects of inhaling high concentration hydrogen on cerebral ischemia re perfusion injury in rats. 中国脑血管病杂志. 2021;18(5):303-310

链接：https://xueshu.baidu.com/usercenter/paper/show?paperid=163v0tf0rb4402c0fp7m0rm0f1271035&site=xueshu_se

皮肤

81.Yang et al. 氢氧混合气对健康人皮肤血流灌注的影响.The effects of hydrogen-oxygen mixed gas on skin blood flow in healthy adults. 中国动脉硬化杂志 2018 年第 26 卷第 6 期. Chin J Arterioscler，Vol 26，No 6，2018.

链接：https://xueshu.baidu.com/usercenter/paper/show?paperid=1n0302b0196c0430d90w0mu0sq434184&site=xueshu_se

眼耳鼻

葡萄膜炎

21.Yan et al.治疗后氢气吸入对内毒素诱导的大鼠葡萄膜炎的影响. Effects of Post-Treatment Hydrogen Gas Inhalation on Uveitis Induced by Endotoxin in Rats. Medical Science Monitor 2018; 24: 3840-3847

链接：https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020745/

听力损失

24.Guowei et al. 隐性听力损失动物模型建立与防护的研究. An Animal Model and Protection of Hidden Hearing Loss. 中华耳科学杂志2015;16(4):462-467

链接：https://www.cnki.com.cn/Article/CJFDTOTAL-ZHER201804007.htm

视网膜缺血再灌注

27.Wu et al. 氢治疗对视网膜缺血再灌注神经损伤的保护作用. Hydrogen postconditioning promotes survival of rat retinal ganglion cells against ischemiareperfusion injury through the PI3KAkt pathway. Biochemical and Biophysical Research Communications 2018; 495(4):2462-2468

链接：https://www.sciencedirect.com/science/article/abs/pii/S0006291X17325482

视网膜

32.Long et al.视网膜分支静脉阻塞(大鼠模型)吸氢后减少VEGF-α表达. Protective effects of hydrogen gas in a rat model of branch retinal vein occlusion via decreasing VEGF-α expression. BMC Ophthalmology 2019 ;19(1):112

链接：https://link.springer.com/article/10.1186/s12886-019-1105-2

耳鸣

76.Jin et al. 氢气吸入治疗急性原发性耳鸣的临床初探. A preliminary clinical study of hydrogen inhalation in the treatment of acute primary tinnitus.中国耳鼻咽喉头颈外.CHIN ARCH OTOLARYNGOL HEAD NECK SURG . 2022;8(29):8

链接：https://xueshu.baidu.com/usercenter/paper/show?paperid=141a0m40s9510c90y6750ay0f6325748&site=xueshu_se

黄斑变性

63.Liang et al.在新生血管年龄相关性黄斑变性小鼠模型中，氢气吸入的抗炎作用及其对激光诱导的脉络膜新生血管的影响。The Anti-Inflammatory Effect of Hydrogen Gas Inhalation and Its Influence on Laser-Induced Choroidal Neovascularization in a Mouse Model of Neovascular Age-Related Macular Degeneration. Int. J. Mol. Sci. 2021, 22(21), 12049

链接：https://www.mdpi.com/1422-0067/22/21/12049

综合叙述性

氢氧安全性

50.Lin et al. 氢，氧混合物用于医疗目的和吸入的叙述性回顾. A narrative review of hydrogen-oxygen mixture for medical purpose and the inhaler thereof. Medical Gas Research 2020;10(1):1-8

链接：https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092144/

治疗理论

54.Camara et al. AMS-H-01生产高剂量氢气，用于治疗疾病. The production of high dose hydrogen gas by the AMS-H-01 for treatment of disease. Medical Gas Research 2016;6(3):164-166

链接：https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110138/

氢氧作用机制

66.Tian et al. 氢是一种新型治疗分子，可调节氧化应激、炎症和细胞凋亡. Hydrogen, a Novel Therapeutic Molecule, Regulates Oxidative Stress, Inflammation, and Apoptosis. Front Physiol. 2021;12:789507.

链接：https://www.frontiersin.org/articles/10.3389/fphys.2021.789507/full

免疫功能

免疫功能

58.Chen et al. 高流量吸入氢气可能会抑制中年参与者的免疫功能：一项自我对照研究. High-flow hydrogen inhalation might suppresses the immune function of middle-aged participants: a self-controlled study. Med Gas Res 2021;11(1):12-17.

链接：https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103974/

肠胃道

胰腺炎

60.Li et al.预先吸入富含氢的气体可预防轻油霉素诱导的小鼠急性胰腺炎，同时增强胰腺Hsp60蛋白的表达。Pre-inhalation of hydrogen-rich gases protect against caerulein-induced mouse acute pancreatitis while enhance the pancreatic Hsp60 protein expression. BMC Gastroenterology. 2021; (21):178

链接：https://link.springer.com/article/10.1186/s12876-021-01640-9

肠道细菌

79.Liu et al. 氢气通过抗炎和抗氧化作用以及调节肠道微生物群改善急性酒精性肝损伤. Hydrogen gas ameliorates acute alcoholic liver injury via anti-inflammatory and antioxidant effects and regulation of intestinal microbiota. Int Immunopharmacol. 2023;120:110252

链接:

https://www.sciencedirect.com/science/article/abs/pii/S1567576923005738

脂肪肝

脂肪肝

73.Tao et al. 氢氧吸入治疗非酒精性脂肪肝的随机、安慰剂对照临床试验. A randomized, placebo-controlled clinical trial of hydrogen/oxygen inhalation for non-alcoholic fatty liver disease. J Cell Mol Med. 2022;00:1–11.

链接：https://onlinelibrary.wiley.com/doi/full/10.1111/jcmm.17456